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1.
Opt Lett ; 35(3): 354-6, 2010 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-20125719

RESUMO

What we believe to be the first demonstration of isotope-specific detection of a low-Z and low density object shielded by a high-Z and high-density material using monoenergetic gamma rays is reported. The isotope-specific detection of LiH shielded by Pb and Al is accomplished using the nuclear resonance fluorescence line of L7i at 478 keV. Resonant photons are produced via laser-based Compton scattering. The detection techniques are general, and the confidence level obtained is shown to be superior to that yielded by conventional x-ray and gamma-ray techniques in these situations.

2.
Skin Therapy Lett ; 12(8): 1-3, 2007 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-18026675

RESUMO

Atypical presentations of typical dermatological conditions are common in human immunodeficiency virus (HIV). This article will focus on three specific topics: eosinophilic folliculitis, psoriasis, and cutaneous mycoses. Their unique presentations in HIV and treatments are discussed.


Assuntos
Dermatomicoses/fisiopatologia , Foliculite/fisiopatologia , Infecções por HIV/complicações , Psoríase/fisiopatologia , Antifúngicos/uso terapêutico , Terapia Antirretroviral de Alta Atividade , Antivirais/uso terapêutico , Dermatomicoses/tratamento farmacológico , Dermatomicoses/etiologia , Foliculite/tratamento farmacológico , Foliculite/etiologia , Infecções por HIV/tratamento farmacológico , Humanos , Psoríase/tratamento farmacológico , Psoríase/etiologia
3.
Phys Rev E Stat Nonlin Soft Matter Phys ; 67(6 Pt 2): 066501, 2003 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16241361

RESUMO

VISA (Visible to Infrared SASE Amplifier) is a high-gain self-amplified spontaneous emission (SASE) free-electron laser (FEL), which achieved saturation at 840 nm within a single-pass 4-m undulator. The experiment was performed at the Accelerator Test Facility at BNL, using a high brightness 70-MeV electron beam. A gain length shorter than 18 cm has been obtained, yielding a total gain of 2 x 10(8) at saturation. The FEL performance, including the spectral, angular, and statistical properties of SASE radiation, has been characterized for different electron beam conditions. Results are compared to the three-dimensional SASE FEL theory and start-to-end numerical simulations of the entire injector, transport, and FEL systems. An agreement between simulations and experimental results has been obtained at an unprecedented level of detail.

4.
Phys Rev E Stat Nonlin Soft Matter Phys ; 66(3 Pt 2B): 036503, 2002 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-12366273

RESUMO

Electron beam microbunching in both the fundamental and second harmonic in a high-gain self-amplified spontaneous emission free-electron laser (SASE FEL) was experimentally characterized using coherent transition radiation. The microbunching factors for both modes (b(1) and b(2)) approach unity, an indication of FEL saturation. These measurements are compared to the predictions of FEL simulations. The simultaneous capture of the microbunching and SASE radiation for individual micropulses correlate the longitudinal electron beam structure with the FEL gain.

5.
Phys Rev Lett ; 88(20): 204801, 2002 May 20.
Artigo em Inglês | MEDLINE | ID: mdl-12005570

RESUMO

Nonlinear harmonic radiation was observed using the VISA self-amplified, spontaneous emission (SASE) free-electron laser (FEL) at saturation. The gain lengths, spectra, and energies of the three lowest SASE FEL modes were experimentally characterized. The measured nonlinear harmonic gain lengths and center spectral wavelengths decrease with harmonic number, n, which is consistent with nonlinear harmonic theory. Both the second and third nonlinear harmonics energies are about 1% of the fundamental energy. These experimental results demonstrate for the first time the feasibility of using nonlinear harmonic SASE FEL radiation to produce coherent, femtosecond x rays.

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